- 주저자 : Cha J, Kim YS(김영선), Rhim H, Lim HK, Choi D, Lee MW
- 영문 제목 : Radiofrequency ablation using a new type of internally cooled electrode with an adjustable active tip: An experimental study in ex vivo bovine and in vivo porcine livers
- 한글 제목 : 활성전극의 길이 조정이 가능한 새로운 고주파열치료 전극: 적출 소간과 생체 돼지간을 이용한 동물실험 연구
- 저널 : Eur J Radiol
- 연도 : 2011
- 권 / 쪽 : 77 / 516-521
- 초록
PURPOSE:
The aims of this study were to evaluate the performance of radiofrequency (RF) ablation using a new type of internally cooled RF electrode with an adjustable active tip in an ex vivo bovine liver model and to determine if adjustment of the active tip length makes a significant difference in the size of ablation zone in an in vivo porcine liver model.
MATERIALS AND METHODS:
We performed ex vivo experiments by producing 100 RF ablation zones in 40 extracted bovine livers using a new type of RF electrode that had an adjustable active tip (adjustable electrode) (n = 50) and a conventional internally cooled electrode (conventional electrode) (n = 50). We also performed an in vivo study with the induction of 30 RF ablation zones in ten living porcine livers using the adjustable electrode with 2 cm (n = 15) and 3 cm (n = 15) active tip adjustments. The size (three perpendicular diameters), volume and ratio of the two axes of the ablation zone were macroscopically evaluated and were compared.
RESULTS:
For the ex vivo study using a 2 cm and 3 cm active tip, there was no significant difference in ablation performance between the use of conventional and adjustable electrodes. For the use of the conventional and adjustable electrodes with 2 cm active tip, respectively, the volume was 10.75 ± 3.43 cm(3) versus 10.64 ± 3.25 cm(3) and the ratio of the two axes was 1.24 ± 0.16 versus 1.30 ± 0.17; p > 0.05. For the use of the conventional and adjustable electrodes with 3 cm active tip, respectively, the volume was 21.17 ± 4.09 cm(3) versus 21.48 ± 3.51 cm(3) and the ratio of the two axes was 1.28 ± 0.12 versus 1.28 ± 0.07; p > 0.05. For the in vivo study using the adjustable electrode, the ablation volume with the 2 cm adjustment was significantly smaller as compared to the 3 cm adjustment (5.29 ± 2.22 cm(3) versus 13.44 ± 4.25 cm(3); p < 0.05) with no statistical difference for the ratio of the two axes (1.44 ± 0.22 versus 1.49 ± 0.24; p > 0.05).
CONCLUSION:
Using a new type of internally cooled RF electrode, we could induce different volumes of the RF ablation zone by means of adjusting the length of the exposed active tip, where performance was similar to the use of a conventional internally cooled RF electrode."